Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...

Autism spectrum disorder is complex; it present differently in different patients, and the causes are still unclear, even though hundreds of small ... | Genetics And Genomics ...

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...

In what might be a surprise for some, the male sex chromosome is far more complex than its female counterpart. This is why it’s taken scientists so long to work out exactly what makes a male a male.

Research co-led by King's College London and Sidra Medicine, Qatar, has produced the most detailed map to date of large-scale genetic differences in the Qatari population, providing a clearer picture ...

Virginia Tech entomologists have developed a chromosome map for about half of the genome of the mosquito Aedes agypti, the major carrier of dengue fever and yellow fever. With the map, researchers can ...

The Y chromosome is inherited only through the paternal line. Sons receive their Y chromosome exclusively from their father.

PacBio launched CiFi, a method combining 3C and HiFi long-read sequencing to generate chromosome scale, haplotype resolved genome assemblies in one run.

This image depicts the detection of structural variants (SVs) at low sequencing coverage in both unique and repetitive regions by genomic proximity mapping (GPM), compared with other SV-calling ...