As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...

DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...

Particle therapy, including proton and carbon ion radiotherapy, represents a major advancement in cancer treatment due to its ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes) and is ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601 Sequencing data from 56,965 ...

Artios Pharma collected $115 million from an oversubscribed series D that will support its growing ambitions for its pipeline of DNA damage response (DDR)-targeting cancer prospects. The biotech is ...