PTIR calculates the rates at which originally monomeric proteins are transformed into aggregates at various temperatures under initial-rate settings. Utilizing SMSLS for identical conditions generates ...

Protein-based therapeutics have transformed treatments for numerous diseases, yet their production remains highly complex and cost-intensive [1][2],[3][4]. Downstream processing (DSP), including ...

Fused in sarcoma (FUS) is a multifunctional RNA-binding protein that regulates transcription and mRNA processing inside cells. It is mainly present in the nucleus with traces in the cytoplasm.

When confirming antibody concentrations, sizing up proteins, or seeking the perfect formulation for a next-gen biologic, traditional approaches leave researchers tied to the lab bench for way too long ...

Raghu R. Chivukula, MD, Ph.D., a physician-investigator in the Departments of Medicine & Surgery and the Center for Genomic Medicine at Massachusetts General Hospital and Harvard Medical School, is ...