Université de Strasbourg and partners report that adding structural variants and small insertion–deletion mutations to single-nucleotide polymorphism analyses raised trait heritability estimates by 14 ...

OBJECTIVE: Venous thromboembolism could be manifested as deep venous thrombosis or pulmonary embolism. The aim of this study was to assess the impact of genetic risk factors including prothrombin ...

In a recent study published in the journal Nutrients, researchers in Canada reviewed the genetic mechanisms contributing to individual variation in vitamin D (VD) levels in circulation. Humans can ...

In this study, the authors sequenced emm89 serotype genomes of clinical isolates from patients in Japan, where the number of invasive Group A Streptococcus (GAS), especially those of the emm89 ...

Ayodeji Adegunsoye, MD, PhD, MSc, discusses how emerging genetic insights like telomere-related mutations may reshape disease management in idiopathic pulmonary fibrosis (IPF). These markers not only ...

Huntington’s disease remains a major challenge, but allele-selective gene editing offers new hope. By targeting only the mutant gene, this approach could provide a one-time, durable treatment. Life ...

Our study shows how whole-genome duplication (WGD), a massive and naturally widespread macromutation, increases population genetic variation both through point mutations and via large structural ...

Version of Record: This is the final version of the article. The authors developed an extension to the pairwise sequentially Markov coalescent model that allows to simultaneously analyze multiple ...

Thank you for your research on burden heritability. I have truly benefited from it, and now I have some questions I'd like to consult you on. This is my input file, and it actually contains four ...