DFI stands for "DNA Fragmentation Index," which is a measure of the quality of the DNA or genetic material of the sperm “. DFI indicates the proportion of sperm in a semen sample that have damaged DNA. Sperm with high levels of DNA damage may have reduced fertility potential and may be more likely to result in miscarriage, genetic abnormalities in offspring, or even infertility. To know more, reach out to a fertility specialist at NOVA IVF. Call 1800 313 5677 #fertilityjourney #fertilitytreatmen

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🧬 Causes of Sperm DNA Damage 🧬 Did you know that sperm DNA fragmentation (SDF) can result from various internal and external factors? Here are some key contributors: 1️⃣ **Problems During Sperm Production**: Errors in spermatogenesis, like defective chromatin packaging and abortive apoptosis, can lead to damaged DNA in sperm. 2️⃣ **Post-Testicular Damage**: Once sperm leave the testes, they can become vulnerable to oxidative stress, especially if stored in the epididymis for too long. 3️⃣ **Li

Is Sperm also responsible ? Sperm DNA damage (DNA fragmentation) affects both fertility and pregnancy outcomes. • It can cause infertility, poor embryo quality, and IVF/ICSI failure even when semen analysis is normal. • It is linked to recurrent miscarriage, failed implantation, preeclampsia, preterm birth, and low birth weight. • Common causes: oxidative stress, smoking, varicocele, infections, heat, toxins, and advanced paternal age. • A DNA fragmentation index (DFI) >25–30% is usually conside